n.a progressive form of presenile dementia that is similar to senile dementia except that it usually starts in the 40s or 50s; first symptoms are impaired memory which is followed by impaired thought and speech and finally complete helplessness

同義詞：Alzheimer's diseaseAlzheimer'sAlzheimers

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Asso...
Schenk, D. et al. Immunization with A attenuates Alzheimer's disease-like pathology in the PDAPP mouse. Nature 400, 173-177
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer′s, Prion, and Parkinson′s Diseases and Amyotrophic Lateral Sclerosis)
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide forma...
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a pract...
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice.